Dangers come but dangers also go, and when they do, the brain has an “all-clear” signal that teaches it to extinguish its fear. A new study in mice by MIT neuroscientists shows that the signal is the release of dopamine along a specific interregional brain circuit. The research pinpoints a potentially critical mechanism of mental health, restoring calm when it works, but prolonging anxiety or even post-traumatic stress disorder when it doesn’t.

Since high school, Alex Bardon has been interested in biology. As an undergrad at Caltech, she was introduced to the world of computer science. Systems neuroscience was the place where those interests met.

“While individual neurons can perform some cool computations, when they are grouped in a system, these whole new phenomena emerge that you can't get at the single neuron level. I found that fascinating,” she says.

Bardon is now a third-year graduate student in Brain and Cognitive Sciences at MIT, where she is co-advised by professors Emery Brown and Earl Miller at The Picower Institute for Learning and Memory and studies how the synchrony between different brain areas changes, causing these areas to become more or less connected, during anesthesia. 

The Department of Brain and Cognitive Sciences celebrated faculty, staff, teaching, mentorship, and academic excellence in several recent ceremonies.