Aging Brain Initiative Seminar Series with Dr. Bradley Hyman
Description
The clinical picture of Alzheimer's is a slowly progressive downhill course of increasing depth and breadth of cognitive failure. Neuropathologically this is paralleled by increasing tangles and neuronal loss in a hierarchical distribution in the limbic and, later, association areas. We have recently proposed a "spreading" hypothesis of tangles to account for the slow elaboration of tangle pathology across the brain, and have developed in vitro and in vivo models to explore this biology
Speaker Bio
Dr. Bradley Hyman is the Director of the Massachusetts Alzheimer’s Disease Research Center at MGH and the John B. Penney, Jr. Professor of Neurology at Harvard Medical School. He also directs the Alzheimer’s Laboratory unit at Mass General Institute for Neurological Disease, with the goal of understanding the neuropathophysiologic and genetic factors that underlie dementia. Dr. Hyman is author of over 600 papers. Dr. Hyman received his M.D. and Ph.D. from University of Iowa, and he has received the Metropolitan Life Award, the Potamkin Prize, an NIH Merit award, and an Alzheimer’s Association Lifetime Achievement Award. He is a member of the National Academy of Medicine.