Dr. Wojciech Krezel graduated from the Wroclaw University of Technology, Poland in 1992 and completed his PhD in molecular genetics and developmental biology at Strasbourg’s Louis Pasteur University in 1997. As a Fellow of the Human Frontier Science Program (HFSP), he joined the laboratory of Professor Paul Chapman at Cardiff University (1998-2001, Wales, UK) for post-doctoral training in neuroscience where he gained experience in electrophysiology and animal behavior. From 2001 to 2005, he contributed to the design, validation and running of the behavioral phenotyping platform at Mouse Clinical Institute (ICS) in Illkirch, France. In 2005 he joined the French National Institute of Health and Medical Research (INSERM) and has led research projects at IGBMC, focusing on the role of nuclear hormone receptors in the development and functions of the central nervous system.

His pioneering discoveries include the identification of the role of retinoid receptor signaling in brain functions including motor control, affective behaviors and memory functions. Upstream and downstream control of such signaling is the focus of his present interests and has allowed the recent identification of the first endogenous retinoid acting as the physiological ligand of retinoid X receptor and, moreover, the filing of three patents focused on new strategies of treatment of Central Nervous System (CNS) disorders.