Date: Friday, May 16, 2025
Time: 12:00pm – 1:00pm
Location: Simons Center Conference room 46-6011 + Zoom (https://mit.zoom.us/j/91490329119)

Speaker: Dr. Christopher Fell
Affiliation: Simons Postdoctoral Fellow, Abudayyeh & Gootenberg Lab, Harvard Medical School; Gene and Cell Therapy Institute, Mass General Brigham

Talk title: Repurposing natural enzymes for large genomic edits

Abstract: Treating human genetic disorders remain a large, unmet need. Gene editing technologies are rapidly advancing to clinics but are limited in the scale of edits that they can make. In this talk, I will present recent advances in the emerging gene editing modality called Programmable Gene Integration (PGI), which may be able to treat genetic diseases through gene replacement or supplementation.