This workshop is suitable for postdocs and graduate students who would like to learn how to use Picower Epigenome Bioinformatics Resources. No prior knowledge in this field is needed to participate in this workshop. The workshop will consist of a short lecture followed by demonstrations.

Under the Picower director’s leadership, Bioinformatics unit has built a comprehensive epigenome webserver/database for studying neurogenesis and pathogenesis of neurological and psychiatric disorders. Currently, the Picower Epigenome Database includes several hundred processed GWAS, DNA methylation, ChIP-Seq, ATAC-Seq, Hi-C, ChIA-PET data produced from different neuronal cell types, cultured cell lines, postmortem brain tissues of four well-studied species: Homo_sapien, Macaca_mulatta, Mus_musculus and Rattus_norvegicus. The database is updated monthly with newly publicly available epigenome data. A web-based browser interface has been implemented for investigators to easily access the database and explore genes /genomic regions of their research interests (neurological diseases, neurodevelopment, ageing, activity-dependent stimulation, and etc.). Another web-based analyzer interface generates quantitative aggregation plots / heatmaps.

Please note that the workshop will last for 1 hour, and all the participants are REQUIRED to bring their own laptop computers for hands-on practice.